Treating Sick Muscles After ACL Injury: Translating the Science into the Clinic

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This presentation was recorded at NATA 2022 in Philadelphia and featured in our 2023 Encore.

Abstract:
Atrophy that occurs after anterior cruciate ligament (ACL) injury continues despite being actively engaged in exercise. Recognizing the multitude of factors and cascade of events that are present and negatively influencing the regulation of muscle mass after ACL injury will likely enable clinicians to design more effective interventions. This session will present the mechanisms by which muscle mass is lost after ACL injury and evidence in support of alternative exercise interventions to optimize muscle recovery after injury.

Learning Objectives:

  • Develop a rehabilitation protocol that directly targets insufficiencies in neural activity and muscle morphology after ACL injury
  • Summarize how mechanically engaging muscle is beneficial to targeting adaptations in muscle size and composition
  • Understand the time course of muscle dysfunction after injury so that the timing of the intervention is the most effective

Level:
Advanced

Domain(s):

  • Domain 4: Therapeutic Intervention

CEUs:
1.0 Category A

Keywords: rehabilitation, neuromuscular, muscle atrophy, ACL, injury, recovery

Enhanced Access On-Demand Course Expiration:
Access to this course will expire at the end of the membership year on December 31 at 11:59 p.m. CST.
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Lindsey Lepley, PhD, ATC

Lindsey Lepley, PhD, ATC

Dr. Lindsey Lepley is an associate professor of Athletic Training, director of the Comparative Orthopedic Rehabilitation Laboratory, and co-director of the Orthopedic Rehabilitation & Biomechanics Laboratory at the University of Michigan School of Kinesiology. Dr. Lepley’s research program focuses on elucidating the mechanisms that regulate skeletal muscle strength, activation, and structure after traumatic joint injury to establish interventions that optimize muscle recovery. To advance clinical practice, her research group utilizes non-invasive animal injury models and human subject research to design, test, and translate new sports medicine strategies from conception to practice. This rare blend of scientific approaches empowers her lab to make fundamental discoveries about musculoskeletal health that can change rehabilitation. This work has received several research awards, is currently funded by NIH/NIAMS, and has been selected for featured presentations at national and international scientific meetings.
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